Kinases

Proteases

Other targets

In Silico Discovery of Beta-Secretase Inhibitors
J. Am. Chem. Soc., ASAP Article, March 30, 2006
> PubMed

Novel Yeast Cell-Based Assay To Screen for Inhibitors of Human Cytomegalovirus Protease in a High-Throughput Format
Antimicrobial Agents and Chemotherapy, February 2006, p. 565-571, Vol. 50, No. 2.
> PubMed

Discovery of Cell-Permeable Non-Peptide Inhibitors of Beta-Secretase by High-Throughput Docking and Continuum Electrostatics Calculations
Journal of Medicinal Chemistry; July 8, 2005
> PubMed

Yeast growth selection system for the identification of cell-active inhibitors of beta-secretase
Biochim Biophys Acta; September 6, 2004; 1674(1):29-39
> PubMed

Searching for the most effective screening system to identify cell-active inhibitors of beta-secretase
Biol Chem; June 2004; 385(6):481-5
> PubMed

Human β-secretase activity in yeast detected by a novel cellular growth selection system
Biochimica et Biophysica Acta 25493 (2002) 1-12; December 4, 2002
> PubMed

Proteolytic Enzymes as Therapeutic Targets
European Biopharmaceutical Review; 2002
> PDF